Vitamin D and reproductive disorders: a comprehensive review with a focus on endometriosis

Vitamin D and reproductive disorders: a comprehensive review with a focus on endometriosis

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Abstract Vitamin D is a fat-soluble steroid hormone that was initially known only for regulating calcium and phosphorus levels and maintaining bone health.However, it was later discovered that many organs express vitamin D metabolizing enzymes and have a ligand for vitamin D, which regulates the expression of an extensive assortment of genes.As a result, vitamin D is indispensable for the proper function of organs, and its deficiency is believed to be a critical factor in symptoms and click here disorders such as cardiovascular diseases, autoimmune diseases, and cancers.The significance of vitamin D in reproductive tissues was recognized later, and studies have revealed its crucial role in male and female fertility, as well as proper reproductive function during pregnancy.Vitamin D deficiency has been identified as a risk factor for infertility, gonadal cancers, pregnancy complications, polycystic ovary syndrome, and endometriosis.

However, data investigating the association between vitamin D levels and reproductive disorders, including endometriosis, have encountered inconsistencies.Therefore, the present study aims to review existing research on the soiebiologique.com effect of vitamin D on proper reproductive function, and the role of deficiency in reproductive diseases and specifically focuses on endometriosis.